Nephroprotective Efficacy of Selenium and Zinc Against Potassium Dichromate-Induced Renal Toxicity in Pregnant Wistar Albino Rats

Autor:	Anfal Fedala, Ounassa Adjroud, Omar Bennoune, Salwa Abid-Essefi, Abdelhamid Foughalia, Rim Timoumi
Rok vydání:	2021
Předmět:	Endocrinology Diabetes and Metabolism Biochemistry (medical) Clinical Biochemistry General Medicine Kidney Biochemistry Antioxidants Rats Inorganic Chemistry Oxidative Stress Selenium Zinc Pregnancy Animals Female Potassium Dichromate Rats Wistar Biomarkers
Zdroj:	Biological trace element research. 200(11)
ISSN:	1559-0720
Popis:	Hexavalent chromium (CrVI) compounds are potent toxicants commonly used in numerous industries. Thus, potential toxic effects and health hazards are of high relevance. Selenium (Se) and zinc (Zn) are known for their antioxidant and chemoprotective properties. However, little is known about their protective effects against CrVI-induced renal damage during pregnancy. In this context, the present study aimed to investigate the protective efficacy of these two essential elements against potassium dichromate-induced nephrotoxicity in pregnant Wistar Albino rats. Female rats were divided into control and four treated groups of six each receiving subcutaneously on the 3rd day of pregnancy, K
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa67351a158bb2daa480860be1150fc https://pubmed.ncbi.nlm.nih.gov/35066750 Zobrazit plný text záznamu Full text from SpringerLink