Comparison of patients hospitalized with COVID-19, H7N9 and H1N1

Autor: Gongqi Chen, Shenghong Tang, Guoyu Tan, Jinyu Xia, Yuanli Chen, Lisi Deng, Xinghua Li, Chao-Hui Zhao, Xiaohe Li, Li Ding, Jianfeng Lan, Xi Liu, Jing Yuan, Wen-Tao Luo
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
viruses
Comorbidity
030204 cardiovascular system & hematology
Influenza A Virus
H7N9 Subtype
medicine.disease_cause
Logistic regression
Influenza A Virus
H1N1 Subtype
0302 clinical medicine
Risk Factors
030212 general & internal medicine
Respiratory system
Child
Lung
Coronavirus
Aged
80 and over
lcsh:Public aspects of medicine
H1N1
virus diseases
General Medicine
Middle Aged
Virus Shedding
Hospitalization
Infectious Diseases
Child
Preschool
Disease Progression
Female
Research Article
Adult
medicine.medical_specialty
Adolescent
Isolation (health care)
Comparison
Virus
lcsh:Infectious and parasitic diseases
H7N9
Young Adult
03 medical and health sciences
Internal medicine
Influenza
Human
medicine
Humans
lcsh:RC109-216
Risk factor
Aged
business.industry
SARS-CoV-2
Public health
Public Health
Environmental and Occupational Health
COVID-19
lcsh:RA1-1270
Tropical medicine
business
Zdroj: Infectious Diseases of Poverty, Vol 9, Iss 1, Pp 1-9 (2020)
Infectious Diseases of Poverty
ISSN: 2049-9957
Popis: Background There is an urgent need to better understand the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for that the coronavirus disease 2019 (COVID-19) continues to cause considerable morbidity and mortality worldwide. This paper was to differentiate COVID-19 from other respiratory infectious diseases such as avian-origin influenza A (H7N9) and influenza A (H1N1) virus infections. Methods We included patients who had been hospitalized with laboratory-confirmed infection by SARS-CoV-2 (n = 83), H7N9 (n = 36), H1N1 (n = 44) viruses. Clinical presentation, chest CT features, and progression of patients were compared. We used the Logistic regression model to explore the possible risk factors. Results Both COVID-19 and H7N9 patients had a longer duration of hospitalization than H1N1 patients (P P = 0.01). H7N9 patients had similar patterns of lymphopenia, neutrophilia, elevated alanine aminotransferase, C-reactive protein, lactate dehydrogenase, and those seen in H1N1 patients, which were all significantly different from patients with COVID-19 (P P P = 0.78). For severe cases, the meantime from illness onset to severity was 8.0 days for COVID-19 vs 5.2 days for H7N9 (P P = 0.02). Multivariate analysis showed that chronic heart disease was a possible risk factor (OR > 1) for COVID-19, compared with H1N1 and H7N9. Conclusions The proportion of severe cases were higher for H7N9 and SARS-CoV-2 infections, compared with H1N1. The meantime from illness onset to severity was shorter for H7N9. Chronic heart disease was a possible risk factor for COVID-19.The comparison may provide the rationale for strategies of isolation and treatment of infected patients in the future.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje