The Genetics of MDD – A Review of Challenges and Opportunities

Autor: Marianna R. Bevova, Peter Heutink, Eva C. Verbeek, Witte J.G. Hoogendijk
Přispěvatelé: Clinical genetics, NCA - Neurobiology of mental health
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Verbeek, E C, Bevova, M R, Hoogendijk, W J G & Heutink, P 2014, ' The Genetics of MDD – A Review of Challenges and Opportunities ', Journal of Depression and Anxiety, vol. 3, 150, pp. 150 . https://doi.org/10.4172/2167-1044.1000150
Journal of Depression and Anxiety, 3:150
ISSN: 2167-1044
DOI: 10.4172/2167-1044.1000150
Popis: Major depressive disorder (MDD) is a psychiatric disorder characterized among others by prolonged depressed mood, a loss of interest in enjoyable activities, psychomotor retardation and various cognitive symptoms. Although exact numbers of prevalence may differ between various western countries, partly due to a social taboo of the illness, the life-time prevalence in the USA and Western Europe lies around 15%. Women are more likely to be struck by MDD than men, often with a first episode between 30-40 years of age, with a smaller second peak around 50-60 years of age. Although MDD may appear as a “stand alone” disease, 33% of patients with a chronic illness report symptoms of major depression. In addition, approximately 72% of patients diagnosed with MDD also have a second mental illness diagnosed, in most cases generalized anxiety disorder or a social phobia. Although some patients may only experience a single episode, MDD often appears in multiple episodes.
Databáze: OpenAIRE