Triglyceride levels and risk of type 2 diabetes mellitus: a longitudinal large study
| Autor: | Elad Goldberg, Eytan Cohen, Ilan Krause, Amani Beshara, Moshe Garty, Pearl Lilos |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty 030209 endocrinology & metabolism 030204 cardiovascular system & hematology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences chemistry.chemical_compound Young Adult 0302 clinical medicine Risk Factors Diabetes mellitus Internal medicine Medicine Humans Longitudinal Studies Risk factor Triglycerides Aged Triglyceride business.industry Type 2 Diabetes Mellitus Retrospective cohort study General Medicine Fasting Stepwise regression Middle Aged medicine.disease Impaired fasting glucose Endocrinology Logistic Models chemistry Diabetes Mellitus Type 2 Large study Female business Follow-Up Studies |
| Zdroj: | Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 64(2) |
| ISSN: | 1708-8267 |
| Popis: | The relationship between triglyceridemia and diabetes mellitus remains unclear. This study evaluated the risk of diabetes and impaired fasting glucose associated with a wide range of triglyceride levels. A longitudinal retrospective study was carried out employing data from a screening center between the years 2000 and 2012. Inclusion criteria were absence of diabetes at baseline and attendance at the center at least twice over a 5-year period. Participants were divided by fasting blood glucose level (normal/impaired) at the first visit. A total of 5085 participants were eligible for the study. Of the 4164 normoglycemic participants at baseline, 40 (0.96%) had diabetes and 998 (24%) had impaired fasting glucose by the end of the study. On stepwise logistic regression analysis, every 10 mg/dL increase in triglyceride level significantly increased the risk of diabetes by 4% and of impaired fasting glucose by 2% (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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