Recurrent and Metastatic Cutaneous Squamous Cell Carcinomas in a Cohort of 774 Patients in Finland
| Autor: | Johanna Palve, Tiina Luukkaala, Niina Korhonen, Julius Itkonen, Erna Snellman, Juha Jernman, Henni Häihälä, Leea Ylitalo |
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| Přispěvatelé: | HUS Inflammation Center, Clinicum, Department of Dermatology, Allergology and Venereology |
| Rok vydání: | 2020 |
| Předmět: |
Male
squamous cell carcinoma Oncology Invasion depth medicine.medical_specialty Skin Neoplasms Cutaneous squamous cell carcinoma Cell Dermatology Disease GUIDELINES DIAGNOSIS DISEASE Metastatic tumours Metastasis PROGNOSTIC-FACTORS Risk Factors Internal medicine lcsh:Dermatology medicine Humans metastasis Neoplasm Invasiveness Finland Aged Retrospective Studies Aged 80 and over Scalp business.industry Medical record DEATH Torso General Medicine Middle Aged lcsh:RL1-803 medicine.disease 3. Good health medicine.anatomical_structure Head and Neck Neoplasms 3121 General medicine internal medicine and other clinical medicine Cohort RISK-FACTORS Carcinoma Squamous Cell Female Neoplasm Recurrence Local business Precancerous Conditions keratinocyte carcinoma recurrent tumour |
| Zdroj: | Acta Dermato-Venereologica, Vol 100, Iss 8, p adv00121 (2020) |
| ISSN: | 1651-2057 |
| Popis: | Recognising patients with high risk cutaneous squamous cell carcinomas is essential in planning effective monitoring. The aim of this study was to determine the rate of local recurrences and metastases of cutaneous squamous cell carcinomas in a previously defined patient cohort in Finland. Pathology database search was performed to identify cutaneous squamous cell carcinoma patients and their medical records were reviewed. The cohort consisted of 774 patients with 1,131 cutaneous squamous cell carcinoma tumours. Overall, 4.2% (48/1,131) of the tumours were metastatic and 2.2% (25/1,131) had a local recurrence. Three of the metastatic tumours and 8 of the recurrent tumours had an invasion depth of ≤ 2 mm. The majority of metastases (28/48; 58%) were found within 3 months of the diagnosis of cutaneous squamous cell carcinoma. In conclusion, our study demonstrated recurrences and metastases even in the case of thin cutaneous squamous cell carcinomas and in high-risk cases close monitoring should be organised during the first years after diagnosis. |
| Databáze: | OpenAIRE |
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