Trading certainty for speed - How much uncertainty are decisionmakers and guideline developers willing to accept when using rapid reviews: An international survey

Autor: Agustín Ciapponi, Gernot Wagner, Gerald Gartlehner, Judith Greimel, Barbara Nussbaumer-Streit
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
Epidemiology
Ciencias de la Salud
UNCERTAINTY
DECISION-MAKING
0302 clinical medicine
Guideline developer
Interquartile range
Surveys and Questionnaires
030212 general & internal medicine
media_common
lcsh:R5-920
Evidence-Based Medicine
030503 health policy & services
GUIDELINE DEVELOPER
Uncertainty
Certainty
Middle Aged
Otras Ciencias de la Salud
Systematic review
SYSTEMATIC REVIEW
Practice Guidelines as Topic
purl.org/becyt/ford/3 [https]
Female
0305 other medical science
lcsh:Medicine (General)
DECISIONMAKER
Research Article
Adult
medicine.medical_specialty
CIENCIAS MÉDICAS Y DE LA SALUD
media_common.quotation_subject
Rapid review
Decision Making
Health Informatics
Sample (statistics)
03 medical and health sciences
purl.org/becyt/ford/3.3 [https]
Young Adult
medicine
Humans
Decisionmaker
Health policy
RAPID REVIEW
Aged
Actuarial science
business.industry
Public health
International survey
Reproducibility of Results
Guideline
Review Literature as Topic
business
Decision-making
Zdroj: BMC Medical Research Methodology, Vol 17, Iss 1, Pp 1-8 (2017)
BMC Medical Research Methodology
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Popis: Background: Decisionmakers and guideline developers demand rapid syntheses of the evidence when time sensitive evidence-informed decisions are required. A potential trade-off of such rapid reviews is that their results can have less reliability than results of systematic reviews that can lead to an increased risk of making incorrect decisions or recommendations. We sought to determine how much incremental uncertainty about the correctness of an answer guideline developers and health policy decisionmakers are willing to accept in exchange for a rapid evidence-synthesis. Methods: Employing a purposive sample, we conducted an international web-based, anonymous survey of decisionmakers and guideline developers. Based on a clinical treatment, a public health, and a clinical prevention scenario, participants indicated the maximum risk of getting an incorrect answer from a rapid review that they would be willing to accept. We carefully reviewed data and performed descriptive statistical analyses. Results: In total, 325 (58.5%) of 556 participants completed our survey and were eligible for analysis. The median acceptable incremental risk for getting an incorrect answer from a rapid review across all three scenarios was 10.0% (interquartile range [IQR] 5.0-15.0). Acceptable risks were similar for the clinical treatment (n = 313, median 10.0% [IQR 5.0-15.0]) and the public health scenarios (n = 320, median 10.0% [IQR 5.0-15.0]) and lower for the clinical prevention scenario (n = 312, median 6.5% [IQR 5.0-10.5]). Conclusions: Findings suggest that decisionmakers are willing to accept some trade-off in validity in exchange for a rapid review. Nevertheless, they expect the validity of rapid reviews to come close to that of systematic reviews. Fil: Wagner, Gernot. Danube University Krems; Alemania Fil: Nussbaumer Streit, Barbara. Danube University Krems; Alemania Fil: Greimel, Judith. Universidad de Hohenheim; Alemania Fil: Ciapponi, Agustín. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Gartlehner, Gerald. Danube University Krems; Alemania
Databáze: OpenAIRE