Change of the State of the Natural Antioxidant Barrier of a Body and Psychological Parameters in Patients Aged above 60
| Autor: | Beata Augustyńska, Martyna Porzych, Emilia Mikołajewska, Rafał Bilski, Mirosława Szark-Eckardt, Marcin Porzych, Magdalena Żyła, Katarzyna Porzych, Kornelia Kędziora-Kornatowska, Daria Kupczyk |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine Aging Antioxidant Article Subject media_common.quotation_subject medicine.medical_treatment medicine.disease_cause Biochemistry Antioxidants Neglect 03 medical and health sciences 0302 clinical medicine Humans Medicine In patient Psychological testing lcsh:QH573-671 Aged media_common Aged 80 and over lcsh:Cytology business.industry Working memory Healthy subjects Cell Biology General Medicine Middle Aged Alertness 030104 developmental biology Female business 030217 neurology & neurosurgery Oxidative stress Research Article Clinical psychology |
| Zdroj: | Oxidative Medicine and Cellular Longevity Oxidative Medicine and Cellular Longevity, Vol 2017 (2017) |
| ISSN: | 1942-0900 |
| DOI: | 10.1155/2017/6568501 |
| Popis: | Background. The goal of this study is to assess the natural antioxidant barrier of the organism and selected psychological aspects of the aging process in patients above 60 years old.Methods. The study included a total of 52 patients aged above 60 (mean age 67 ± 3.4) and 32 healthy subjects (mean age 22 ± 3.4) as a control group. All patients underwent psychological assessment using Test of Attentional Performance version 2.3 (TAP 2.3, four subtests: alertness, cross-modal integration, neglect with central task, and working memory) and biochemical analysis of venous blood concerning values of the selected parameters of oxidative stress (HT, GSH, GPXOS, GPXRBC, GRRBC1, SODRBC1, MDARBC1, NO2−/NO3−, and CP).Results. Disorders of attention were observed mainly in elderly people, but an assumption that elderly people have developed more efficient ways of working memory use than younger people may be true. Results showed the reduced effectiveness of the body’s natural antioxidant barrier in elderly people. Moderate positive and negative correlations among parameters of oxidative stress and psychological parameters were observed in the control group.Discussion. Intensification of the attention deficits and oxidative stress may be observed as one of the pathogenic factors of age-dependent diseases. |
| Databáze: | OpenAIRE |
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