Increased Sensitization to Mold Allergens Measured by Intradermal Skin Testing following Hurricanes
| Autor: | David S. Hurst, Diego Saporta |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Allergy medicine.medical_specialty Adolescent Article Subject Health Toxicology and Mutagenesis Population Group B 03 medical and health sciences Young Adult 0302 clinical medicine medicine Hypersensitivity Humans 030212 general & internal medicine Respiratory system Young adult education Sensitization Asthma Retrospective Studies Skin Tests education.field_of_study 030505 public health New Jersey business.industry Cyclonic Storms Incidence (epidemiology) lcsh:Public aspects of medicine Incidence Public Health Environmental and Occupational Health Fungi lcsh:RA1-1270 Allergens Middle Aged medicine.disease Dermatology Surgery medicine.anatomical_structure Female 0305 other medical science business Research Article |
| Zdroj: | Journal of Environmental and Public Health Journal of Environmental and Public Health, Vol 2017 (2017) |
| ISSN: | 1687-9805 |
| DOI: | 10.1155/2017/2793820 |
| Popis: | Objective. To report on changes in sensitivity to mold allergens determined by changes in intradermal skin testing reactivity, after exposure to two severe hurricanes. Methods. A random, retrospective allergy charts review divided into 2 groups of 100 patients each: Group A, patients tested between 2003 and 2010 prior to hurricanes, and Group B, patients tested in 2014 and 2015 following hurricanes. Reactivity to eighteen molds was determined by intradermal skin testing. Test results, age, and respiratory symptoms were recorded. Chi-square test determined reactivity/sensitivity differences between groups. Results. Posthurricane patients had 34.6 times more positive results (p<0.0001) at weaker dilutions, all tested molds were found to be more reactive, and 95% had at least one positive test versus only 62% before the hurricanes (p<0.0001); average mold reactivity was 55% versus 16% while 17% of patients reacted to the entire panel versus none before the hurricanes (p<0.0001). The posthurricane population was younger (p<0.001) and included more patients with asthma or lower respiratory symptoms (p<0.05). Conclusion. Reactivity and sensitization to mold allergens increased compared to patients before the hurricanes. This supports climatologists’ hypothesis that environmental changes resulting from hurricanes can be a health risk as reflected in increased allergic sensitivities and symptoms and has significant implications for physicians treating patients from affected areas. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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