Survival and Recurrence Rates after Resection for Hepatocellular Carcinoma in Noncirrhotic Livers

Autor: Gabriele Meyer, Eirini I. Brokalaki, Klaus J. Schmitz, Hauke Lang, Massimo Malagó, Christian Bertona, Georgios C. Sotiropoulos, Andreas Paul, Christoph E. Broelsch, Andrea Frilling
Rok vydání: 2007
Předmět:
Zdroj: Journal of the American College of Surgeons. 205:27-36
ISSN: 1072-7515
DOI: 10.1016/j.jamcollsurg.2007.03.002
Popis: BACKGROUND: Hepatocellular carcinoma occurring in noncirrhotic livers is rare. The purpose of this article was to evaluate the outcomes and prognostic factors after hepatectomy in this setting. STUDY DESIGN: Between June 1998 and May 2005, 83 patients underwent liver resection for hepatocellular carcinoma in noncirrhotic livers at our institution. Preoperative treatment data, intraoperative details, pathologic findings, and information on tumor recurrence, treatment of recurrence, and survival were available for 80 of these patients. RESULTS: Postresection, the 3- and 5-year-survival rates were 48% and 30%, respectively. After R0 resection (n=66), the calculated 3- and 5-year-survivals were 54% and 39%, compared with 23% and 0%, respectively, after R1/2-resection (p
Databáze: OpenAIRE