Temporal order memory differences in Alzheimer's disease and vascular dementia
| Autor: | Steven M. Platek, Douglas L. Chute, Thomas Swirsky-Sacchetti, David J. Libon, Ludo Scheffer, Benjamin M. Hampstead, Stephen T. Moelter |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Neuropsychological Tests Serial Learning Severity of Illness Index Statistics Nonparametric Alzheimer Disease medicine Dementia Humans Attention Vascular dementia Aged Sequential access memory Aged 80 and over Psychiatric Status Rating Scales Memory Disorders Recall Working memory Dementia Vascular Cognitive disorder Cognition Recognition Psychology medicine.disease Clinical Psychology Neurology Disease Progression Female Neurology (clinical) Alzheimer's disease Psychology Neuroscience |
| Zdroj: | Journal of clinical and experimental neuropsychology. 32(6) |
| ISSN: | 1744-411X |
| Popis: | Determining the order of events is essential for accurate memory recollection: an ability previously linked to both frontal and medial temporal functioning. Frontal-subcortical and medial temporal dysfunction typify vascular dementia (VaD) and Alzheimer's disease (AD), respectively. Therefore, we assessed patients' ordering abilities using a novel sequencing task that progressively increased memory load. VaD patients made more errors and selected more previously encountered stimuli than did AD. Curve analysis revealed a general decline in ordering for VaD whereas error production in AD is more dependent on memory load. These findings generally support the role of frontal-subcortical functioning in temporal order memory. |
| Databáze: | OpenAIRE |
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