2-hydroxyethylierung von oligo(iminoethylen)en und deren überführung in oligo-[N-(2-chloroethyl)iminoethylen]e

Autor:	Werner Kern, Christian Mannschott, Hartwig Höcker
Rok vydání:	1981
Předmět:	chemistry.chemical_compound Thionyl chloride Ethylene oxide chemistry Hydrochloride organic chemicals Polymer chemistry Molecule neoplasms
Zdroj:	Die Makromolekulare Chemie. 182:3369-3369
ISSN:	0025-116X
DOI:	10.1002/macp.1981.021821140
Popis:	Oligo[N-(2-chloroethyl)iminoethylene]s (8) were synthesized as potential antitumor agents like their low molecular weight analogues. It was found that oligo(iminoethylene)s (5) can be 2-hydroxyethylated with ethylene oxide and subsequently transformed into oligo[N-(2-chloroethyl)iminoethylene hydrochloride]s (14) with thionyl chloride. The stability of the free oligomers 8 was found to decrease with the number of N-2-chloroethyl groups in the molecule.
Databáze:	OpenAIRE
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