Being overweight or obese is associated with decreased mortality in critically ill patients: A retrospective analysis of a large regional Italian multicenter cohort
| Autor: | Gilberto Fiore, Cristina Elia, Silvano Cardellino, Claudia Filippini, Luciana Mascia, V. Marco Ranieri, Bruno Barberis, Yasser Sakr, Sergio Livigni |
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| Přispěvatelé: | Yasser Sakr, Cristina Elia, Luciana Mascia, Bruno Barberi, Silvano Cardellino, Sergio Livigni, Gilberto Fiore, Claudia Filippini, Vito Marco Ranieri |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Critical Illness Comorbidity Overweight Critical Care and Intensive Care Medicine Body Mass Index law.invention BMI Sex Factors Critically ill patients Thinness law Sepsis Internal medicine 80 and over medicine Prognosis Age Factors Aged Aged 80 and over Female Humans Intensive Care Units Italy Middle Aged Multicenter Studies as Topic Obesity Retrospective Studies Elective surgery business.industry nutritional and metabolic diseases Retrospective cohort study medicine.disease Intensive care unit Surgery n/a Cohort medicine.symptom Underweight business Body mass index |
| Popis: | PURPOSE: To describe the epidemiology of obesity in a large cohort of intensive care unit (ICU) patients and study its impact on outcomes. METHODS: All 3902 patients admitted to one of 24 ICUs in the Piedmont region of Italy from April 3 to September 29, 2006, were included in this retrospective analysis of data from a prospective, multicenter study. RESULTS: Mean body mass index (BMI) was 26.0 ± 5.4 kg/m(2): 32.8% of patients had a normal BMI, 2.6% were underweight, 45.1% overweight, 16.5% obese, and 2.9% morbidly obese. ICU mortality was significantly (P < .05) lower in overweight (18.8%) and obese (17.5%) patients than in those of normal BMI (22%). In multivariate logistic regression analysis, being overweight (OR = 0.73; 95%CI: 0.58-0.91, P = .007) or obese (OR = 0.62; 95%CI: 50.45-0.85, P = .003) was associated with a reduced risk of ICU death. Being morbidly obese was independently associated with an increased risk of death in elective surgery patients whereas being underweight was independently associated with an increased risk of death in patients admitted for short-term monitoring and after elective surgery. CONCLUSIONS: In this cohort, overweight and obese patients had a reduced risk of ICU death. Being underweight or morbidly obese was associated with an increased risk of death in some subgroups of patients. |
| Databáze: | OpenAIRE |
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