Maternal cardiovascular function in the prediction of fetal distress in labor: a prospective cohort study
Autor: | Alexander Makatsariya, Pavjola Maqina, Maria Luviso, Silvio Tartaglia, Jia Li Angela Lu, Giuseppe Rizzo, Ilenia Mappa |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Obstetrics business.industry Infant Newborn Pregnancy Outcome Obstetrics and Gynecology Hemodynamics Perinatal outcome Diagnostic accuracy Stroke volume medicine.disease Settore MED/49 Fetal Distress Ultrasonography Prenatal Umbilical Arteries Pregnancy Pediatrics Perinatology and Child Health Cohort medicine Fetal distress Humans Female Prospective Studies Prospective cohort study business |
Zdroj: | The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(25) |
ISSN: | 1476-4954 |
Popis: | To explore the strength of association and the diagnostic accuracy of maternal hemodynamic parameters detected noninvasively in predicting an adverse perinatal outcome in labor.Prospective cohort study of singleton women undergoing antepartum care at 37-39 weeks of gestation. A noninvasive ultrasonic cardiac output monitor (USCOM®) was used for cardiovascular assessment. The study outcome was a composite score of adverse perinatal outcome, which included at least one of the following variables: Cesarean or instrumental delivery for abnormal fetal heart monitoring, umbilical artery pH7.10 or admission to neonatal special care unit. Attending clinicians were blinded to maternal cardiovascular indices. Multivariate logistic regression and area under the curve (AUC) analyses were used to test the diagnostic accuracy of different maternal and ultrasound characteristics in predicting adverse perinatal outcome.A total of 133 women were recruited. The rate of adverse perinatal outcome was 25.6% (34/133). Women who delivered without abnormal perinatal outcome (controls) were more likely to be parous, compared to those who had an adverse perinatal outcome (44.4 vs. 73.5%;Pre-labor modifications of maternal cardiovascular variables are associated with adverse perinatal outcome. However, their predictive accuracy for perinatal compromise is low, and thus their use as standalone screening test for adverse perinatal outcome in singleton pregnancies at term is not supported. |
Databáze: | OpenAIRE |
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