CHORIORETINAL WHITE DOT LESIONS IN EYES WITH MULTIFOCAL CHOROIDITIS AND TILTED DISK SYNDROME WITH INFERIOR STAPHYLOMA
| Autor: | Sarah Mrejen, Salomon Y. Cohen, Camille Jung, Polina Astroz, Eric H Souied |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Choroiditis genetic structures Optic Disk Posterior pole Optic disk Fundus (eye) Young Adult 03 medical and health sciences 0302 clinical medicine Retinal Diseases Macula Lutea Ophthalmology Optic Nerve Diseases Humans Medicine Eye Abnormalities Fluorescein Angiography Aged Retrospective Studies medicine.diagnostic_test business.industry Multifocal Choroiditis Staphyloma General Medicine Middle Aged Fluorescein angiography medicine.disease eye diseases Choroidal neovascularization Case-Control Studies 030221 ophthalmology & optometry Female sense organs medicine.symptom business Tomography Optical Coherence 030217 neurology & neurosurgery |
| Zdroj: | Retina. 37:154-160 |
| ISSN: | 0275-004X |
| Popis: | PURPOSE To assess the influence of tilted disk syndrome (TDS) and inferior staphyloma on the macular clinical expression of MFC. METHODS Medical charts of patients with MFC examined since 2009 were reviewed retrospectively. All patients underwent standard examination and multimodal imaging including fundus color photography, fundus autofluorescence, and spectral domain optical coherence tomography. Two groups of patients were compared : Group 1 with TDS and inferior staphyloma and Group 2 without. The number of MFC spots were counted and normalized to the surface area in a circle centered about the fovea. In Group 1, the number of lesions inside the staphyloma was compared with that outside the staphyloma. RESULTS At baseline, 8 eyes in Group 1 had a mean (±SD) higher number of chorioretinal lesions outside the staphyloma (14.5 [±7.2]) than within the staphyloma (5 [±5.5]) (P = 0.017). All 11 eyes in Group 2 had chorioretinal lesions homogeneously distributed in the posterior pole. Eyes with TDS and inferior staphyloma developed choroidal neovascularization more frequently (6/8 eyes) than eyes without TDS (5/11 eyes) (P = 0.026). CONCLUSION Inferior staphyloma associated with TDS could modulate the clinical expression of the inflammatory and neovascular process in eyes with MFC. |
| Databáze: | OpenAIRE |
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