Further studies on the structure of vaccinia virus

Autor: Wilbur Fiske Noyes
Rok vydání: 1962
Předmět:
Zdroj: Virology. 18:511-516
ISSN: 0042-6822
DOI: 10.1016/0042-6822(62)90051-x
Popis: The fine structure of the different forms of vaccinia virus observed in the electron microscope by means of negative contrast is presented and discussed. The mature intact particle has a surface covering of 150-A projections which are easily denatured to form surface cords. The cords and projections are probably formed from small ringlike or tubular subunits covered with an adherent envelope. Penetration of the phosphotungstate into the particle reveals a double membrane system and an internal nucleoid. Particles ruptured by high frequency sound show internal filaments of about 20 A in diameter which may be the DNa macromolecules of the virus.
Databáze: OpenAIRE