Autor:	N. Zielke, B. A. Edgar, M. L. DePamphilis
Rok vydání:	2013
Předmět:	DNA Replication Polyploidy Mice Cell Cycle Cyclin E Cyclin-Dependent Kinase 2 Animals Drosophila Endoreduplication General Biochemistry Genetics and Molecular Biology Perspectives
Zdroj:	Cold Spring Harbor perspectives in biology. 5(1)
ISSN:	1943-0264
Popis:	Developmentally programmed polyploidy occurs by at least four different mechanisms, two of which (endoreduplication and endomitosis) involve switching from mitotic cell cycles to endocycles by the selective loss of mitotic cyclin-dependent kinase (CDK) activity and bypassing many of the processes of mitosis. Here we review the mechanisms of endoreplication, focusing on recent results from Drosophila and mice.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf52579676340e253a3b245ea908f6a6 https://pubmed.ncbi.nlm.nih.gov/23284048 Zobrazit plný text záznamu