Further evidence for both functional and structural microcompartmentation within the membranes of two associated organelles, mitochondrion and endoplasmic reticulum

Autor: Odile Gateau-Roesch, Françoise Gasnier, Cédric Simonot, D. Ardail, Pierre Louisot, J. Guillaud, F. Lerme, G. Febvay
Přispěvatelé: Biologie Fonctionnelle, Insectes et Interactions (BF2I), Institut National de la Recherche Agronomique (INRA)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA), Laboratoire de biologie appliquée, Institut National de la Recherche Agronomique (INRA), Laboratoire Bf2i, Insa, ProdInra, Migration
Jazyk: angličtina
Rok vydání: 1993
Předmět:
MESH: Amino Acids
Biophysics
Mitochondria
Liver
Mitochondrion
Biology
Endoplasmic Reticulum
Biochemistry
MESH: Multivariate Analysis
Mice
MESH: Cell Compartmentation
MESH: Endoplasmic Reticulum
MESH: Analysis of Variance
Organelle
Cell Compartmentation
[SDV.BBM] Life Sciences [q-bio]/Biochemistry
Molecular Biology
Animals
[SDV.BBM]Life Sciences [q-bio]/Biochemistry
Molecular Biology
MESH: Animals
Amino Acids
Molecular Biology
MESH: Mice
chemistry.chemical_classification
Analysis of Variance
Endoplasmic reticulum
STIM1
Intracellular Membranes
[SDV.EE.IEO] Life Sciences [q-bio]/Ecology
environment/Symbiosis
Cell Biology
Membrane contact site
Mitochondria
Cell biology
Amino acid
MESH: Intracellular Membranes
Membrane
Liver
chemistry
MESH: Subcellular Fractions
Multivariate Analysis
MESH: Mitochondria
Liver
Subcellular Fractions
[SDV.EE.IEO]Life Sciences [q-bio]/Ecology
environment/Symbiosis
Zdroj: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 1993, 195 (3), pp.1365-70
Biochemical and Biophysical Research Communications, Elsevier, 1993, 195 (3), pp.1365-1370
ISSN: 0006-291X
1090-2104
Popis: International audience; We previously demonstrated that the translocation of phospholipids between the mitochondrion and the endoplasmic reticulum occurs via highly specialized membrane microdomains of both organelles that are in situ closely associated. As understanding of the interactions between both organelles requires characterization of the translocation sites organization, we first analysed the amino acid compositions of these sites. Using principal component analysis, we have shown that the translocation sites exhibit characteristic patterns when compared with the membranes from which they are derived. The results are discussed in terms of both functional and structural microcompartmentation within the membranes of mitochondria and endoplasmic reticulum.
Databáze: OpenAIRE
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