Risk Factors for Surgical Site Infection Following Lower Limb Arthroplasty: A Retrospective Cohort Analysis of 3932 Lower Limb Arthroplasty Procedures in a High Volume Arthroplasty Unit
| Autor: | Alistair Ewen, Angela H. Deakin, Almustafa M, Fahd F. Mahmood, Jon Clarke, Frederic Picard |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood transfusion Neutrophils Arthroplasty Replacement Hip medicine.medical_treatment Body Mass Index Young Adult 03 medical and health sciences 0302 clinical medicine Rivaroxaban Risk Factors medicine Humans Surgical Wound Infection Blood Transfusion Orthopedics and Sports Medicine Cyanoacrylates 030212 general & internal medicine Arthroplasty Replacement Knee Aged Retrospective Studies Aged 80 and over 030222 orthopedics business.industry Warfarin Retrospective cohort study Venous Thromboembolism Middle Aged Arthroplasty Surgery Absolute neutrophil count Female Steroids business Complication Cohort study medicine.drug |
| Zdroj: | The Journal of Arthroplasty. 33:1861-1867 |
| ISSN: | 0883-5403 |
| Popis: | Background Surgical site infection (SSI) is a debilitating complication of lower limb arthroplasty with significant morbidity and increased costs. Numerous risk factors are associated with SSI. Methods In an effort to identify novel risk factors for SSI, we undertook a retrospective cohort study of 1832 primary total hip arthroplasties and 2100 primary total knee arthroplasties performed in our high volume arthroplasty unit over a 2-year period. Results Two risk factors were identified for SSI following total hip arthroplasty: body mass index ≥30 and peri-operative blood transfusion. Eight risk factors were identified for SSI following total knee arthroplasty: hypertension, peri-operative blood transfusion, skin closure using 2-octyl cyanoacrylate, use of oral steroids, reduced serum mean cell volume, reduced mean cell hemoglobin, elevated serum neutrophil count, and use of warfarin or rivaroxaban for venous thromboembolism prophylaxis. Conclusions Our work proposes a number of previously undocumented risk factors in relation to SSI. Further investigation is required to ascertain the magnitude of their effect. |
| Databáze: | OpenAIRE |
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