Radiosurgery in treatment of cerebral arteriovenous malformation: Mid-term results of 388 cases from a single center
Autor: | Ramon Katoozpour, Abbas Amirjamshidi, Mohammad Ali Bitaraf, Seyed Abolghasem Mortazavi, Mazyar Azar, Mohsen Nouri |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
medicine.medical_specialty
business.industry Arteriovenous malformation of the brain medicine.medical_treatment Mid term results radiosurgery Arteriovenous malformation General Medicine medicine.disease Single Center Radiosurgery Surgery post-radiosurgery hemorrhage medicine Retrospective analysis Original Article Radiology Endovascular treatment business Large size |
Zdroj: | Asian Journal of Neurosurgery |
ISSN: | 2248-9614 1793-5482 |
Popis: | Background and Objectives: The purpose of this study is to evaluate the outcome and risks of radiosurgery for patients with arteriovenous malformations (AVM) of the brain all treated in a single center in the 3rd world with all its limitations. Materials and Methods: We performed a retrospective analysis of 388 patients with AVM treated with radiosurgery during an 8-year period. Factors associated with increased chance of AVM obliteration or hemorrhages during the follow-up period were analyzed. Results: Among 388 cases included in our series, 74 were Spetzler-Martin (SM) grade IV or V. Forty-four patients (11.3%) experienced post-radiosurgery hemorrhage in their follow-up period. The number of feeders (one/multiple) and deep location of the AVM did not alter the chance of bleeding (P < 0.05). Higher SM grading of the AVM was associated with increased chance of hemorrhage and decreased obliteration rate (P > 0.05) in the mid-term follow up. Conclusions: Our case series showed that radiosurgery can be considered a viable alternative in the treatment of even large AVMs which might not be considered good candidates for surgery or endovascular treatment. Further data including large size lesions are warranted to further support our findings. |
Databáze: | OpenAIRE |
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