Surface-Enhanced Raman Spectroscopy for Bisphenols Detection: Toward a Better Understanding of the Analyte–Nanosystem Interactions
| Autor: | Cristina Gellini, Santiago Sánchez-Cortés, Isabel López-Tocón, Giulietta Smulevich, Juan C. Otero, Claudia Focardi, Maurizio Becucci, Marilena Ricci, Bruno Neri, Eleonora Roschi |
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| Přispěvatelé: | Ministero della Salute, Ministerio de Economía y Competitividad (España), Junta de Andalucía |
| Rok vydání: | 2021 |
| Předmět: |
Analyte
Materials science bisphenol B Bisphenol S General Chemical Engineering bisphenol A Analytical chemistry 02 engineering and technology DFT calculations 01 natural sciences Silver nanoparticle Article lcsh:Chemistry symbols.namesake Bisphenol A bisphenol S Bisphenol B Nanosensor Cyclodextrin General Materials Science Detection limit Hydrogen bond SERS 010401 analytical chemistry Surface-enhanced Raman spectroscopy 021001 nanoscience & nanotechnology 0104 chemical sciences lcsh:QD1-999 cyclodextrin symbols Density functional theory 0210 nano-technology Raman spectroscopy |
| Zdroj: | Digital.CSIC: Repositorio Institucional del CSIC Consejo Superior de Investigaciones Científicas (CSIC) Digital.CSIC. Repositorio Institucional del CSIC instname Nanomaterials Nanomaterials, Vol 11, Iss 881, p 881 (2021) Volume 11 Issue 4 |
| DOI: | 10.13039/501100011011 |
| Popis: | 13 pags., 6 figs., 1 tab. -- This article belongs to the Special Issue Nanomaterials in Surface-Enhanced Raman Spectroscopy Silver nanoparticles functionalized with thiolated β-cyclodextrin (CD-SH) were employed for the detection of bisphenols (BPs) A, B, and S by means of surface-enhanced Raman spectroscopy (SERS). The functionalization of Ag nanoparticles with CD-SH leads to an improvement of the sensitivity of the implemented SERS nanosensor. Using a multivariate analysis of the SERS data, the limit of detection of these compounds was estimated at about 10−7 M, in the range of the tens of ppb. Structural analysis of the CD-SH/BP complex was performed by density functional theory (DFT) calculations. Theoretical results allowed the assignment of key structural vibrational bands related to ring breathing motions and the inter-ring vibrations and pointed out an external interaction due to four hydrogen bonds between the hydroxyl groups of BP and CD located at the external top of the CD cone. DFT calculations allowed also checking the interaction energies of the different molecular species on the Ag surface and testing the effect of the presence of CD-SH on the BPs’ affinity. These findings were in agreement with the experimental evidences that there is not an actual inclusion of BP inside the CD cavity. The SERS sensor and the analysis procedure of data based on partial least square regression proposed here were tested in a real sample consisting of the detection of BPs in milk extracts to validate the detection performance of the SERS sensor. This research was supported by the Italian Ministry of Health, Rome, Italy (IZSLT11/17 RC) (G.S., B.N., and C.F.), MINECO/FEDER (FIS2017-84318-R) (S.S.C.), and by Junta de Andalucía/FEDER (UMA18-FEDERJA-049 and P18-RT-4592) (J.C.O.). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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