Semantic feature disturbance in Alzheimer disease: evidence from an object decision task
| Autor: | Anthony J. Angwin, Kieran Flanagan, Gerard J. Byrne, Helen J. Chenery, David A. Copland |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Disturbance (geology) Computer science Semantic feature Cognitive Neuroscience Context (language use) Neuropsychological Tests Semantics 050105 experimental psychology Task (project management) 03 medical and health sciences 0302 clinical medicine Alzheimer Disease Humans 0501 psychology and cognitive sciences Aged 05 social sciences Cognition General Medicine Distinctive feature Object (computer science) Psychiatry and Mental health Neuropsychology and Physiological Psychology Case-Control Studies Female 030217 neurology & neurosurgery Cognitive psychology |
| Popis: | Background and Objective: It is widely held that semantic disturbance in Alzheimer disease (AD) involves the loss of distinctive features but the relative sparing of nondistinctive features. Many previous studies of semantic feature disturbance have used cognitively challenging tasks with verbal stimuli that allow for potential cognitive confounds. Our objective was to use a task with lower memory demands to investigate distinctive feature disturbance in AD. Methods: We used an object decision task to compare the processing of distinctive and nondistinctive semantic features in people with AD and age-matched controls. The task included six conditions based on the relationship between each prime and target object. We tested the processing of distinctive and nondistinctive features by selectively altering distinctive and nondistinctive semantic features between prime and target pairs. Results: Performance accuracy was significantly lower for participants with AD than for age-matched controls when distinctive features were manipulated, but no difference was found when nondistinctive features were manipulated. Conclusions: Our results provide evidence of semantic content disturbance in AD in the context of a task with low cognitive demands. |
| Databáze: | OpenAIRE |
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