ChemInform Abstract: Reaction of Mercaptoacetate and Halides Containing Activated Methylenes with Thiocarbamoylimidates: A Novel Approach to the Synthesis of Aminothiazole Derivatives

Autor:	Hedi Zantour, B. Baccar, Khaireddine Dridi, M. L. El Efrit
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Ethyl bromoacetate Aminothiazole Benzyl bromide Chemistry Condensation Halide General Medicine Medicinal chemistry Methyl thioglycolate
Zdroj:	ChemInform. 29
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199822094
Popis:	The reaction of N-thiocarbamoylimidates 1 with methyl thioglycolate leads to the formation of 4-arylamino-5-methoxycarbonylthiazoles 2. The condensation of the same imidates 1 on ethyl bromoacetate, benzyl bromide and chloroacetonitrile provides the corresponding 2-arylaminothiazoles 4.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4357072c76aa6212b27ceb3b7e9657 https://doi.org/10.1002/chin.199822094 Zobrazit plný text záznamu Plný text