Variants of Concern Are Overrepresented Among Postvaccination Breakthrough Infections of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Washington State

Autor: John B. Lynch, Elizabeth R. Brown, Alexander L. Greninger, Vanessa A. Makarewicz, Jared Castor, Shah A Mohamed Bakhash, Abbye E McEwen, Allison J Zelikoff, Pavitra Roychoudhury, Estella Whimbey, Seth M. Cohen, Catherine Liu, Adrienne Schippers, Meei-Li Huang, Nandita S Mani, Keith R. Jerome, Chloe Bryson-Cahn, Robert J. Livingston, Kathy Strand, Steven A. Pergam, Noah R. Baker
Rok vydání: 2021
Předmět:
Zdroj: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
ISSN: 1537-6591
1058-4838
Popis: Across 20 vaccine breakthrough cases detected at our institution, all 20 (100%) infections were due to variants of concern (VOCs) and had a median Ct of 20.2 (IQR, 17.1–23.3). When compared with 5174 contemporaneous samples sequenced in our laboratory, VOCs were significantly enriched among breakthrough infections (P < .05).
Databáze: OpenAIRE