Efficient identification and regional positioning of YAC and cosmid clones to human chromosome 21 by radiation fusion hybrids
| Autor: | Dean Nizetic, Hans Lehrach, J. Kumlien, G. Zehetner, Radost Vatcheva, T. Labella |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Genetics
Genetic Markers Genotype Chromosomes Human Pair 21 Genetic Vectors High resolution Chromosome Mapping Biology Hybrid Cells chemistry.chemical_compound chemistry Genetic Techniques Mapping system Cricetinae Cosmid Escherichia coli Animals Humans Identification (biology) Chromosome 21 Chromosomes Artificial Yeast DNA Hybrid |
| Zdroj: | Mammalian genome : official journal of the International Mammalian Genome Society. 5(6) |
| ISSN: | 0938-8990 |
| Popis: | The use of integrated mapping strategies involving bacterial, yeast, and rodent cells as hosts simplifies the construction of maps, which combine long-range order, high resolution, and easy access to the cloned DNA. Radiation-fusion hybrids offer a specially powerful long-range mapping system for human chromosomes. We describe here techniques for establishing a radiation-fusion hybrid map of Chromsome (Chr) 21 q and its integration with local information on YAC and cosmid positions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink