Vaccination coverage in the context of the emerging Yellow Fever threat in French Guiana
| Autor: | Fabien Dubois, Sébastien Linares, Sarah Bailly, Camille Fritzell, Sandrine Fernandes Pellerin, Claude Flamand, Alhassane Toure, Mona Saout, Laurent Filleul, Naïssa Chateau, Mirdad Kazanji |
|---|---|
| Přispěvatelé: | Unité d'Epidémiologie [Cayenne, Guyane française], Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Centre de Recherche Translationnelle - Center for Translational Science (CRT), Institut Pasteur [Paris], DEAL Guyane, Santé publique France - French National Public Health Agency [Saint-Maurice, France], We thank all the field investigators, institutions and collaborators involved in the EPIARBO project., Institut Pasteur [Paris] (IP) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine European People Viral Diseases Overseas department Vaccination Coverage Latin Americans [SDV]Life Sciences [q-bio] RC955-962 Immigration Social Sciences Forests Geographical locations 0302 clinical medicine Sociology MESH: Demography Arctic medicine. Tropical medicine MESH: Child Medicine and Health Sciences Ethnicities Public and Occupational Health French People [MATH]Mathematics [math] Child Socioeconomics MESH: Yellow Fever media_common MESH: Aged Family Characteristics education.field_of_study Schools MESH: Middle Aged Ecology Yellow Fever Vaccine Yellow fever MESH: Vaccination Coverage Middle Aged Vaccination and Immunization Terrestrial Environments French Guiana 3. Good health Europe Vaccination [STAT]Statistics [stat] Infectious Diseases Geography MESH: Young Adult Child Preschool Female Public aspects of medicine RA1-1270 Brazil Research Article Adult MESH: Socioeconomic Factors Adolescent media_common.quotation_subject Immunology 030231 tropical medicine Population Context (language use) MESH: Disease Transmission Infectious Ecosystems Education Young Adult 03 medical and health sciences MESH: Cross-Sectional Studies Yellow Fever parasitic diseases MESH: French Guiana Disease Transmission Infectious medicine MESH: Family Characteristics Humans education Socioeconomic status Aged Demography MESH: Adolescent MESH: Humans Ecology and Environmental Sciences MESH: Child Preschool Public Health Environmental and Occupational Health Biology and Life Sciences MESH: Adult South America medicine.disease MESH: Male MESH: Yellow Fever Vaccine Cross-Sectional Studies 030104 developmental biology Socioeconomic Factors Population Groupings Preventive Medicine People and places MESH: Female |
| Zdroj: | PLoS Neglected Tropical Diseases PLoS Neglected Tropical Diseases, Public Library of Science, 2019, 13 (8), pp.e0007661. ⟨10.1371/journal.pntd.0007661⟩ PLoS Neglected Tropical Diseases, Vol 13, Iss 8, p e0007661 (2019) PLoS Neglected Tropical Diseases, 2019, 13 (8), pp.e0007661. ⟨10.1371/journal.pntd.0007661⟩ |
| ISSN: | 1935-2727 1935-2735 |
| Popis: | Background French Guiana, a French overseas department located in South America between Brazil and Surinam, is the only European territory geographically located in the Amazonian forest complex and is considered endemic for yellow fever (YF). In the context of the emergent threat of YF in Latin America, we conducted a large household cross-sectional survey from June to October 2017 to estimate vaccination coverage in the population and to determine associations with sociodemographic and geographical characteristics. Methodology/Principal findings In total, 1,415 households and 2,697 individuals were included from the 22 municipalities of French Guiana. YF vaccination coverage was estimated at 95.0% (95% CI: 93.4–96.2) in the entire territory but was spatially heterogeneous, with the lowest levels estimated in the western part of the territory along the Surinamese cross-border region, particularly in children under 16 years who were not enrolled in school, immigrant adults and disadvantaged populations with low socioeconomic indexes. Conclusions/Significance Despite the good vaccination coverage against YF in the general population of French Guiana resulting from the compulsory nature of YF vaccination for residents and travelers, there is an urgent need to improve vaccination coverage in vulnerable populations living in the northwestern part of the territory to limit the risk of transmission in the context of the emerging YF threat in South America. Despite the relative rarity of YF and the significant number of infectious and tropical diseases in French Guiana, clinicians should adopt a high index of suspicion for YF, particularly in vulnerable and at-risk populations. Author summary Yellow fever (YF) is the most severe arbovirus to circulate in the Americas. French Guiana, a French overseas department located in South America between Brazil and Surinam, is the only European territory geographically located in the Amazonian forest complex and is considered endemic for YF. We conducted a large general population survey from June to October 2017 to estimate vaccination coverage in the population and to identify target vulnerable populations for catch-up vaccination strategies. In total, 1,415 households and 2,697 individuals were included from the 22 municipalities of French Guiana. YF vaccination coverage was estimated at 95.0% (95% CI: 93.4–96.2) in the entire territory but was spatially heterogeneous, with the lowest levels estimated in the western part of the territory along the Surinamese cross-border region, particularly in children under 16 years who were not enrolled in school, immigrant adults and disadvantaged groups of populations with low socioeconomic indexes. Our findings showed that vaccination campaigns should be prioritized and adapted to improve vaccination coverage among vulnerable populations living in the northwestern part of the territory to limit the risk of transmission in the context of the emerging YF threat in South America. Despite the relative rarity of YF and the significant number of infectious and tropical diseases in French Guiana, clinicians should adopt a high index of suspicion for YF, particularly in vulnerable and at-risk populations. |
| Databáze: | OpenAIRE |
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