Prevention and reversal of inspired water content-induced increased airway resistance

Autor: Hamilton Lh, J. Iravani, E.E. Ward, Melville Gn
Rok vydání: 1973
Předmět:
Zdroj: Respiration; international review of thoracic diseases. 30(6)
ISSN: 0025-7931
Popis: Airway resistance in rats increased when the water content of inspired air was greater than 16g/m3 due to nebulized tap or distilled water. This increase was prevented by atropine intravenously, aerosolized ethanol and bilateral cervical vagotomy. Intravenously administered epinephrine did not prevent water content-induced increases in airway resistance and, if administered after increases in airway resistance had occurred, caused a decrease which was analogous to that caused by time alone. Atropine intravenously, aerosolized ethanol and bilateral cervical vagotomy rapidly reversed the water content-induced increases in airway resistance. The possible causes of water content-induced airway resistance increase are discussed
Databáze: OpenAIRE