Continued Spirometry Changes After Cessation of Exposure in Asbestos-Cement Workers
| Autor: | Beata, Swiątkowska, Wojciech, Sobala, Sobala, Wojciech, Zuzanna, Szubert, Neonila, Szeszenia-Dąbrowska |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Lung Diseases Male Spirometry medicine.medical_specialty Vital capacity Cumulative Exposure medicine.disease_cause Asbestos FEV1/FVC ratio Occupational Exposure Internal medicine medicine Humans Aged medicine.diagnostic_test business.industry Disease progression Public Health Environmental and Occupational Health Middle Aged respiratory system Asbestos cement respiratory tract diseases Occupational Diseases Disease Progression Cardiology Mixed effects Female Poland business circulatory and respiratory physiology |
| Zdroj: | Journal of Occupational & Environmental Medicine. 56:403-408 |
| ISSN: | 1076-2752 |
| DOI: | 10.1097/jom.0000000000000117 |
| Popis: | Objective To assess further progression of spirometry parameters among former asbestos-cement plant workers. Methods The following parameters were assessed: forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and the ratio (FEV1/FVC) using a linear regression model with mixed effects. Results The analysis included 3005 individuals. Spirometrically defined restrictive ventilatory defects were registered in 21.6% of the patients, obstructive defects in 8.3%, whereas mixed changes in 7%. Current smokers had significantly lower levels of FEV1, FVC, and FEV1/FVC and a steeper decline compared with nonsmokers. More rapid progression was also observed along with increasing termination of exposure. Having higher exposure was associated with a slower decline in FEV1 and FEV1/FVC ratios. Conclusions This report indicates that asbestos-cement workers with higher cumulative exposure still had lower mean levels of spirometric parameters, despite cessation of asbestos exposure many years ago. |
| Databáze: | OpenAIRE |
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