Modulation of the volume phase transition temperature of thermo-responsive gels
| Autor: | Aleksey D. Drozdov, J. deClaville Christiansen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Polymers Biomedical Engineering Ionic bonding 02 engineering and technology Mole fraction Phase Transition Biomaterials 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Copolymer medicine Transition Temperature Poly(N N-diethylacrylamide) Swelling chemistry.chemical_classification Temperature Thermo-responsive gel 030206 dentistry Polymer 021001 nanoscience & nanotechnology Monomer chemistry Chemical engineering Volume (thermodynamics) Mechanics of Materials Volume phase transition medicine.symptom 0210 nano-technology Biosensor Gels |
| Zdroj: | Drozdov, A D & Christiansen, J D C 2020, ' Modulation of the volume phase transition temperature of thermo-responsive gels ', Journal of the Mechanical Behavior of Biomedical Materials . https://doi.org/10.1016/j.jmbbm.2020.104215 |
| DOI: | 10.1016/j.jmbbm.2020.104215 |
| Popis: | Thermo-responsive (TR) gels swell substantially below their volume phase transition temperature Tc and shrink above this temperature. Applications of TR gels in controlled drug delivery and their use as biosensors and temperature-triggered soft actuators require fine tuning of Tc. As the critical temperature is independent of the preparation conditions and molar fractions of monomers and cross-linkers, it is modulated by incorporation of (neutral or ionic) monomers and polymer chains into pre-gel solutions for TR gels. A model is developed for the mechanical response and equilibrium swelling of TR gels. Analytical formulas are derived for the effect of molar fraction of comonomers on the volume phase transition temperature Tc in copolymer gels and gels with semi-interpenetrating networks. Adjustable parameters are found by fitting equilibrium swelling diagrams on poly(N,N-diethylacrylamide) gels. Good agreement is demonstrated between predictions of the model and experimental data. |
| Databáze: | OpenAIRE |
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