Manned missions to Mars and chromosome damage
Autor: | G. Obe, R. Facius, I. Johannes, Günther Reitz, Christian Johannes |
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Rok vydání: | 1999 |
Předmět: |
T-Lymphocytes
Lymphocyte Mars Linear energy transfer Biology Radiation Dosage Exploration of Mars Ionizing radiation Dicentric chromosome Exobiology medicine Chromosomes Human Humans Linear Energy Transfer Radiology Nuclear Medicine and imaging Chromosome Aberrations Radiological and Ultrasound Technology business.industry Lymphocyte Biology Chromosome Dose-Response Relationship Radiation Molecular biology Background level medicine.anatomical_structure Astronauts Nuclear medicine business Biologie Space Simulation |
Zdroj: | International Journal of Radiation Biology. 75:429-433 |
ISSN: | 1362-3095 0955-3002 |
Popis: | where dA(t) is the change in A resulting during a Purpose: To estimate the frequencies of dicentric chromosomes in time interval dt from the rate of induction, I(t), and peripheral lymphocytes of astronauts on missions to Mars. the rate of losses, L(t), of aberrant cells. In peripheral Materials and methods: Calculations of expected frequencies of lymphocytes, dicentrics are lost during time after dicentrics are based on dose estimations and lymphocyte biology. irradiation either by cell death and renewal from Results: Frequencies of dicentrics are predicted to be 10‐40 times higher than the background level. |
Databáze: | OpenAIRE |
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