Markhor-derived Introgression of a Genomic Region Encompassing PAPSS2 Confers High-altitude Adaptability in Tibetan Goats

Autor:	Chao Li, Yujiang Wu, Bingchun Chen, Yudong Cai, Jiazhong Guo, Alexander S Leonard, Peter Kalds, Shiwei Zhou, Jingchen Zhang, Ping Zhou, Shangqu Gan, Ting Jia, Tianchun Pu, Langda Suo, Yan Li, Ke Zhang, Lan Li, Myagmarsuren Purevdorj, Xihong Wang, Ming Li, Yu Wang, Yao Liu, Shuhong Huang, Tad Sonstegard, Ming-Shan Wang, Stephen Kemp, Hubert Pausch, Yulin Chen, Jian-Lin Han, Yu Jiang, Xiaolong Wang
Rok vydání:	2022
Předmět:	High altitude Goat Genetics Genomics Hypoxia Genetic introgression Molecular Biology Environmental adaptation Ecology Evolution Behavior and Systematics
Zdroj:	Molecular Biology and Evolution, 39 (12)
ISSN:	1537-1719 0737-4038
Popis:	Understanding the genetic mechanism of how animals adapt to extreme conditions is fundamental to determine the relationship between molecular evolution and changing environments. Goat is one of the first domesticated species and has evolved rapidly to adapt to diverse environments, including harsh high-altitude conditions with low temperature and poor oxygen supply but strong ultraviolet radiation. Here, we analyzed 331 genomes of domestic goats and wild caprid species living at varying altitudes (high > 3000 m above sea level and low Molecular Biology and Evolution, 39 (12) ISSN:0737-4038 ISSN:1537-1719
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befb1d60099ae178c64706da1e981eaa https://pubmed.ncbi.nlm.nih.gov/36382357 Zobrazit plný text záznamu