Twins and endocrinology

Autor: K. V. S. Hari Kumar, KD Modi
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Indian Journal of Endocrinology and Metabolism
Indian Journal of Endocrinology and Metabolism, Vol 18, Iss 7, Pp 48-52 (2014)
ISSN: 2230-9500
2230-8210
Popis: Twins are two independent babies delivered during the same pregnancy and are divided as monozygotic or dizygotic based on their origin. Dizygotic twins are similar to two siblings and have different genetic information. In contrary, monozygotic twins have a similar genetic identity and provide a unique opportunity to evaluate the contribution of genetic and environmental factors of the disease. The endocrine and metabolic disorders affect a large number of the population including the twins. Diabetes, obesity, and autoimmune thyroid disease are the most common endocrine disorders in general practice. It is essential to understand the genetic basis of endocrine disorders for therapy, prognostication and risk assessment for future generations. In this article, we review the endocrine disorders in relation to their occurrence in monozygotic twins to highlight the genetic and environmental contribution.
Databáze: OpenAIRE