Effect of Aibellin, a Peptide Antibiotic, on Propionate Production in the Rumen of Goats
| Autor: | Shigenori Kumazawa, Kanda Mina, Hironobu Saitoh, Takehiro Miwa, Tsuneo Hino |
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| Rok vydání: | 1994 |
| Předmět: |
Dietary Fiber
Molar Rumen animal structures medicine.drug_class Antibiotics chemistry.chemical_compound Animal science Genetics medicine Animals Dry matter Monensin chemistry.chemical_classification Goats Gramicidin Eukaryota Fatty Acids Volatile Anti-Bacterial Agents chemistry Biochemistry Fermentation Propionate Digestion Animal Science and Zoology Propionates Peptides Antimicrobial Cationic Peptides Food Science |
| Zdroj: | Journal of Dairy Science. 77:3426-3431 |
| ISSN: | 0022-0302 |
| Popis: | Aibellin was administered in feed to goats (16 to 18 kg of BW) for 12 d. At 80 mg/d, the molar percentage of propionate in rumen fluid increased significantly in 8 d, and the effect lasted for as long as 10 d after administration ceased. Total VFA concentration, protozoa numbers, and NDF digestibility were not depressed significantly at this dosage but were reduced at 100 mg/d with little further increase in the molar percentage of propionate. Therefore, the optimal dosage of aibellin was 80 mg/d under our experimental conditions. In contrast, monensin (30 mg/d) and gramicidin D (60 mg/d) decreased total VFA concentration and protozoa numbers when supplemented to obtain molar percentages of propionate comparable to 80 mg/d of aibellin. From these results, aibellin may be easier and safer to use than monensin and gramicidin D to modify rumen fermentation. |
| Databáze: | OpenAIRE |
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