Serum vitamin K1 concentrations after oral administration of vitamin K1 in low birth weight infants
| Autor: | M. Bourgeay-Causse, M. Bethenod, M. Guillaumont, R. Trouyez, M. Leclercq, L. Sann |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Oral dose
Vitamin Time Factors Physiology Administration Oral Gestational Age chemistry.chemical_compound Vitamin K deficiency medicine Humans Dosing Chromatography High Pressure Liquid Serum vitamin Blood clotting business.industry Infant Newborn Gestational age Vitamin K 1 Factor VII Infant Low Birth Weight medicine.disease Low birth weight chemistry Pediatrics Perinatology and Child Health Factor X Prothrombin medicine.symptom business |
| Zdroj: | The Journal of pediatrics. 107(4) |
| ISSN: | 0022-3476 |
| Popis: | A study reports the results of serial measurements of serum vitamin K levels in newborn low birthweight infants following an oral dose of 2.0 mg vitamin K. Peak serum levels resulted 6-12 hours after dosing with a 20-fold increase in the median level. The results indicate that normal or a high serum vitamin K can be achieved by the end of the first week in life, but it is notknown whether this dosage is sufficient to maintain normal serun vitamin K levels and normal coagulant activities later on. Prolonged blood clotting, especially in breast-fed infants, is due to vitamin K deficiency and supplementation in newborn infants must be recommended. (wz) |
| Databáze: | OpenAIRE |
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