Manifestation of Left Atrial Events and Interatrial Frequency Gradients in the Surface Electrocardiogram During Atrial Fibrillation: Contributions from Posterior Leads

Autor:	Steven Swiryn, Simona Petrutiu, Westby Fisher, Alan V. Sahakian
Rok vydání:	2009
Předmět:	Male medicine.medical_specialty Radiofrequency ablation Sensitivity and Specificity Pulmonary vein law.invention Left atrial law Physiology (medical) Internal medicine Atrial Fibrillation medicine Humans Diagnosis Computer-Assisted Lead (electronics) Electrodes Aged Aged 80 and over medicine.diagnostic_test business.industry Body Surface Potential Mapping P wave Reproducibility of Results Atrial fibrillation Equipment Design Middle Aged medicine.disease Equipment Failure Analysis Surface electrocardiogram Cardiology Female Cardiology and Cardiovascular Medicine business Electrocardiography
Zdroj:	Journal of Cardiovascular Electrophysiology. 20:1231-1236
ISSN:	1540-8167 1045-3873
Popis:	Background: In most patients, atrial fibrillation (AF) is initiated and maintained by pulmonary vein foci, but the relationship between left atrial (LA) events and the surface electrocardiogram (ECG) is largely unknown. We investigated whether LA events are reflected in the surface ECG and whether additional information can be obtained from recording posterior leads in patients with AF. Methods and Results: In 10 patients undergoing radiofrequency ablation of AF, we identified 103 5-second segments with a significant frequency gradient between right (RA) and left (LA) intraatrial electrograms, or with frequency changes from segment to segment in the same patient. QRS-T cancellation methods were used to isolate atrial activity in the surface ECG and peak frequencies were computed. Peak frequencies of different posterior leads were very similar (6.0 ± 1.3 Hz for V10, 6.0 ± 0.9 Hz for V9, 5.9 ± 1.4 Hz for V8, 6.0 ± 1.3 Hz for V7). We found a strong correlation between V1 and RA and between V9 and LA, 0.89 and 0.88, respectively, while the lowest correlation was found between lead V1 and LA, 0.62, P < 0.0001. Magnitude-squared coherence values were highest between V1 and RA and between V9 and LA. Conclusion: We have demonstrated that, by recording additional surface ECG leads from posterior locations, RA and LA electrical events and interatrial frequency gradients can be monitored noninvasively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee8b56d9d37715b16e8b0be4f808eba https://doi.org/10.1111/j.1540-8167.2009.01523.x Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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