Hydrolytic degradation of azimsulfuron, a sulfonylurea herbicide
| Autor: | Daniela Locati, Giovanna Boschin, Cristina Antonioni, Alessandra D’Agostina, Anna Arnoldi |
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| Rok vydání: | 2006 |
| Předmět: |
Electrospray
Spectrometry Mass Electrospray Ionization Environmental Engineering Magnetic Resonance Spectroscopy medicine.drug_class Health Toxicology and Mutagenesis High-performance liquid chromatography Gas Chromatography-Mass Spectrometry Hydrolysis medicine Environmental Chemistry Chemical decomposition Chromatography High Pressure Liquid Sulfonamides Chromatography Aqueous solution Molecular Structure Chemistry Herbicides Public Health Environmental and Occupational Health General Medicine General Chemistry Carbon-13 NMR Hydrogen-Ion Concentration Pollution Sulfonylurea Pyrimidines Sulfonylurea Compounds Proton NMR Pyrazoles |
| Zdroj: | Chemosphere. 68(7) |
| ISSN: | 0045-6535 |
| Popis: | The chemical degradation of the herbicide azimsulfuron was investigated in aqueous solutions at different pH values. The hydrolysis rate, determined by HPLC analyses, was pH dependent and was much faster in acidic than in neutral or weakly basic conditions. The metabolites formed at different pH values were compared with standards when possible or isolated and identified using ESI-LC-MS/MS, 1 H NMR and 13 C NMR. The two main products of hydrolysis in mild acidic solution were identified as 2-amino-4,6-dimethoxy-pyrimidine and 2-methyl-4-(2-methyl-2H-tetrazol-5-yl)-2H-pyrazole-3-sulfonamide, both produced as a result of the sulfonylurea bridge cleavage. Under basic conditions, a new product, a substituted 2-pyrimidinamine, deriving from the contraction of the sulfonylurea bridge, was isolated and completely characterized for the first time. |
| Databáze: | OpenAIRE |
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