Disseminated intravascular coagulation secondary to advanced pancreatic cancer treated successfully with combination chemotherapy
| Autor: | Donald I. Feinstein, Ramesh K. Ramanathan, Peter Rosen, Cathy Mast |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Oncology
Male Cancer Research medicine.medical_specialty New diagnosis Fibrin Fibrinogen Degradation Products hemic and lymphatic diseases Pancreatic cancer Internal medicine Antineoplastic Combined Chemotherapy Protocols Medicine Humans Aged Disseminated intravascular coagulation business.industry Systemic chemotherapy Heparin Combination chemotherapy General Medicine Disseminated Intravascular Coagulation Middle Aged medicine.disease Advanced cancer Gemcitabine Pancreatic Neoplasms business circulatory and respiratory physiology medicine.drug |
| Zdroj: | Oncology. 87(5) |
| ISSN: | 1423-0232 |
| Popis: | Both solid and hematologic malignancies may be complicated by coagulopathies. Disseminated intravascular coagulation (DIC) in the presence of pancreatic cancer is generally unrecognized and may have fatal consequences. The diagnosis of DIC in a patient with advanced cancer is a poor prognostic indicator. Presented here is a case study consisting of two patients presenting with a new diagnosis of pancreatic cancer complicated by DIC. Aggressive supportive treatment in addition to systemic chemotherapy consisting of gemcitabine and nab-paclitaxel was initiated and DIC was controlled. An early diagnosis of DIC and the administration of systemic chemotherapy with a high response rate and an ability to reduce tumor bulk rapidly may offer some patients the probability of recovery. |
| Databáze: | OpenAIRE |
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