Recurrence of pseudomyxoma peritonei within the inguinal canal
| Autor: | Paul H. Sugarbaker, Rodrigo Gomes da Silva, Jacobo Cabanas, Mohan Verghese, Paulo Goldstein |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Inguinal Canal Hernia Inguinal 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Ascites medicine Pseudomyxoma peritonei Humans Hernia Peritoneal Neoplasms Aged business.industry General Medicine Perioperative Middle Aged medicine.disease Pseudomyxoma Peritonei Inguinal canal Adenocarcinoma Mucinous Surgery Inguinal hernia medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Adenocarcinoma Mucinous Tumor medicine.symptom Neoplasm Recurrence Local business Tomography X-Ray Computed |
| Zdroj: | Tumori. 91(6) |
| ISSN: | 0300-8916 |
| Popis: | Aim and Background Tumor appearing in an inguinal hernia sac indicates widespread carcinomatosis with ascites. A new onset hernia is a common clinical presentation of pseudomyxoma peritonei syndrome arising in an appendiceal mucinous tumor. Recurrence of pseudomyxoma peritonei within the inguinal region was previously reported in only a single patient. We present five patients with a recurrence of pseudomyxoma peritonei tumor nodules in the inguinal region following cytoreductive surgery and attempt to understand the etiology of this treatment failure. Methods and Study Design From a database of 910 patients with mucinous appendiceal tumors with peritoneal dissemination who had definitive treatment, five patients who had disease recurrence within the inguinal region were identified. The clinical histories were studied and presented in order to make future recommendations regarding the management of these patients. Results Five patients with ages ranging 39 to 67 years had a mucinous tumor in the inguinal region as a recurrence after a previous cytoreductive surgery combined with perioperative intraperitoneal chemotherapy. One of them had separate recurrence in both right and left inguinal regions. All these patients were made disease-free by the reoperative surgery with a sacrifice of the testicle in four. None have evidence of a recurrence of an inguinal hernia despite the lack of formal repair. Conclusion At the time of initial cytoreductive surgery the surgeon should be aware of the inguinal region as a possible site of relapse. This may be more problematic in patients who have had prior surgery with mucoid fluid in a hernia as the presenting sign of pseudomyxoma peritonei. Inguinal recurrences should be removed with clear margins even if orchiectomy is required. |
| Databáze: | OpenAIRE |
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