Supplementary Figures S1 through S4 from The Intratumoral Balance between Metabolic and Immunologic Gene Expression Is Associated with Anti–PD-1 Response in Patients with Renal Cell Carcinoma

Autor: Suzanne L. Topalian, Janis M. Taube, Drew M. Pardoll, Charles G. Drake, Leslie Cope, Chris Cheadle, Jinshui Fan, Theresa S. Pritchard, Haiying Xu, George J. Netto, Robert A. Anders, Ludmila Danilova, Alan E. Berger, Tracee L. McMiller, Maria Libera Ascierto
Rok vydání: 2023
DOI: 10.1158/2326-6066.22537261.v1
Popis: Figure S1: Extraction of paraffin-embedded PD-L1+ RCC tissues for RNA isolation. Figure S2: Molecules previously found to be up-regulated in PD-L1+ vs. PD-L1(-) melanomas are not differentially expressed in PD-L1+ RCCs from patients with divergent clinical outcomes after anti-PD-1 therapy. Figure S3: Gene expression in RCC cell lines. Figure S4: In silico analyses of TCGA RCC data do not demonstrate significant associations between UGT1A6 gene expression and overall survival or clinical stage.
Databáze: OpenAIRE