Rapid differential diagnosis between subarachnoid hemorrhage and traumatic lumbar puncture by D-dimer assay
| Autor: | Antonio Guerrero-Espejo, Francisco Javier Lirón-Hernández, Pedro Luis Estela-Burriel, Maria Lirios Juliá-Sanchis |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Subarachnoid hemorrhage Traumatic lumbar puncture Adolescent Clinical Biochemistry Spinal Puncture D-dimer assay Diagnosis Differential Fibrin Fibrinogen Degradation Products Cerebrospinal fluid Xanthochromia medicine Humans cardiovascular diseases Child Aged Aged 80 and over business.industry Biochemistry (medical) Infant Middle Aged Subarachnoid Hemorrhage medicine.disease Child Preschool Erythrocyte Count Differential diagnosis business |
| Zdroj: | Clinical chemistry. 53(5) |
| ISSN: | 0009-9147 |
| Popis: | Subarachnoid hemorrhage (SAH) and traumatic lumbar puncture (TLP) are both associated with blood-tinged cerebrospinal fluid (CSF). It is often difficult if not impossible to distinguish between SAH and TLP (1)(2) by available CSF tests such as ( a ) measurement of xanthochromia of the supernatant after centrifugation, ( b ) counting of erythrocytes in the first and last tubes of collected CSF, or ( c ) searching of CSF microscopically for crenated erythrocytes (3)(4)(5). We investigated the measurement of D-dimer (DD) in CSF and evaluated DD measurement as a means to distinguish between SAH and TLP. We measured DD in CSF with the coagulation analyzer STA Compact ® by the immunoturbidimetric assay, STA Liatest D-DI® (Roche Diagnostics). Erythrocyte counts were performed by optical microscopy with a Fuchs-Rosenthal … |
| Databáze: | OpenAIRE |
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