Drosophila telomeres: new views on chromosome evolution
| Autor: | Ky Lowenhaupt, K L Traverse, Mary Lou Pardue, Olga N. Danilevskaya, F Slot |
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| Rok vydání: | 1996 |
| Předmět: |
Transposable element
Genetics biology Base Sequence Retroelements Heterochromatin ved/biology Retroposon ved/biology.organism_classification_rank.species Molecular Sequence Data Chromosome Retrotransposon Telomere biology.organism_classification Evolution Molecular Drosophilidae Animals Drosophila Model organism |
| Zdroj: | Trends in genetics : TIG. 12(2) |
| ISSN: | 0168-9525 |
| Popis: | In Drosophila, chromosome ends (telomeres) are composed of telomere-specific transposable elements (the retroposons HeT-A and TART). These elements are a bona fide part of the cellular machinery yet have many of the hallmarks of retrotransposable elements and retroviruses, raising the possibility that parasitic transposable elements and viruses might have evolved from mechanisms that the cell uses to maintain its chromosomes. It is striking that Drosophila, the model organism for many discoveries in genetics, development and molecular biology (including the classical concept of telomeres), should prove to have chromosome ends different from the generally accepted model. Studies of these telomere-specific retrotransposable elements raise questions about conventional wisdom concerning not only telomeres, but also transposable elements and heterochromatin. |
| Databáze: | OpenAIRE |
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