Fat necrosis mimicking B-cell lymphoma: a PET/CT and FDG study
| Autor: | Ron Fraser, Chirag Jani, Suresh Lakhanpal, Clifford Church, Abdelfatihe Belakhlef |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Vincristine Lymphoma B-Cell Diagnosis Differential Fluorodeoxyglucose F18 medicine Humans Radiology Nuclear Medicine and imaging Fat necrosis Fat Necrosis B-cell lymphoma PET-CT medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Lymphoma Positron emission tomography Positron-Emission Tomography Rituximab Radiology Differential diagnosis Radiopharmaceuticals business Tomography X-Ray Computed medicine.drug |
| Zdroj: | Clinical nuclear medicine. 33(4) |
| ISSN: | 0363-9762 |
| Popis: | F-18 fluoro-2-deoxyglucose positron emission tomography combined with computed tomography (FDG and PET/CT) is increasingly becoming the standard in staging and restaging patients with a range of malignancies including B-cell lymphoma. However, there are well-known pitfalls in PET/CT with FDG imaging, which comprise infection, inflammation, physiological variants, and benign pathologic conditions. Fat necrosis is the result of death of adipose tissue from disease, injury, or pathologic conditions. We describe a case of false positive PET/CT and FDG scan in a patient with fat necrosis mimicking B-cell lymphoma after 6 cycles of rituximab with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) treatment. In interpreting PET/CT and FDG images with inconsistency in lesion response, fat necrosis should be considered in the differential diagnosis. |
| Databáze: | OpenAIRE |
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