Predicted Versus Observed Peak Oxygen Consumption After Major Pulmonary Resection

Autor: Alessandro Brunelli, Michele Salati, Francesco Xiumé, Majed Refai, Cecilia Pompili, Armando Sabbatini
Rok vydání: 2012
Předmět:
Zdroj: The Annals of Thoracic Surgery. 94:222-225
ISSN: 0003-4975
DOI: 10.1016/j.athoracsur.2012.03.034
Popis: Background The aim of this study was to verify the accuracy of predicted postoperative peak V ˙ O 2 in predicting the actual peak V ˙ O 2 after major pulmonary resection. Methods This was a prospective longitudinal series of 110 consecutive patients who underwent lobectomy (101 patients) or pneumonectomy (9 patients), with complete preoperative and postoperative (3 months) cardiopulmonary exercise testing (CPET). Predicted postoperative peak V ˙ O 2 was calculated by subtracting from the preoperative peak V ˙ O 2 the contribution of unobstructed pulmonary segments removed during operation. Predicted postoperative peak V ˙ O 2 and actual postoperative peak V ˙ O 2 were compared by the paired sign test. Results The average value of preoperative peak V ˙ O 2 was 16.8 mL/kg/min or 64.1% of predicted. The actual value of postoperative peak V ˙ O 2 was 15.9 mL/kg/min or 64.4% of predicted. The actual postoperative peak V ˙ O 2 was higher than the predicted postoperative peak V ˙ O 2 (15.9 versus 13.1 mL/kg/min; p p V ˙ O 2 less than 10 mL/kg/min, 19 had an actual postoperative peak V ˙ O 2 greater than 10 mL/kg/min (average value 13.3 mL/kg/min). All 11 patients with a predicted postoperative peak V ˙ O 2 less than 35% of predicted had an actual postoperative peak V ˙ O 2 greater than 35% of predicted (average value, 55.8%). Conclusions The prediction of postoperative peak V ˙ O 2 using the segmental technique was inaccurate. The use of predicted postoperative peak V ˙ O 2 for patient selection must be cautioned against; future studies are warranted to refine its estimation.
Databáze: OpenAIRE