Impact of blood glucose abnormalities on outcomes and disease severity in patients with severe sepsis: An analysis from a multicenter, prospective survey of severe sepsis

Autor: Atsushi Shiraishi, Kiyotsugu Takuma, Takehiko Tarui, Shigeki Kushimoto, Kazuma Yamakawa, Satoshi Gando, Ryosuke Tsuruta, Tomohiko Masuno, Yasuhiro Otomo, Satoshi Fujimi, Joji Kotani, Toshihiko Mayumi, Junichi Sasaki, Kohji Okamoto, Yuichiro Sakamoto, Seitaro Fujishima, Taka-aki Nakada, Hiroto Ikeda, Yutaka Umemura, Akiyoshi Hagiwara, Masashi Ueyama, Toru Hifumi, Naoshi Takeyama, Toshikazu Abe, Yasukazu Shiino, Norio Yamashita, Hiroshi Ogura, Shin-Ichiro Shiraishi, Daizoh Saitoh
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Blood Glucose
Male
Physiology
Pathology and Laboratory Medicine
Severity of Illness Index
0302 clinical medicine
Endocrinology
Medicine and Health Sciences
030212 general & internal medicine
Prospective Studies
Prospective cohort study
Aged
80 and over
Multidisciplinary
Organic Compounds
Mortality rate
Monosaccharides
Drugs
Middle Aged
Shock
Septic
Blood Sugar
Body Fluids
Chemistry
Blood
Shock (circulatory)
Physical Sciences
Medicine
Female
medicine.symptom
Anatomy
Research Article
medicine.medical_specialty
Death Rates
Endocrine Disorders
Science
Carbohydrates
Blood sugar
Hypoglycemics
Hypoglycemia
Sepsis
03 medical and health sciences
Signs and Symptoms
Population Metrics
Diagnostic Medicine
Internal medicine
Diabetes mellitus
medicine
Diabetes Mellitus
Humans
Hypoglycemic Agents
Mortality
Aged
Pharmacology
Population Biology
business.industry
Septic shock
Organic Chemistry
Chemical Compounds
Biology and Life Sciences
030208 emergency & critical care medicine
medicine.disease
Glucose
Severe Sepsis
Metabolic Disorders
business
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 3, p e0229919 (2020)
ISSN: 1932-6203
Popis: Background Dysglycemia is frequently observed in patients with sepsis. However, the relationship between dysglycemia and outcome is inconsistent. We evaluate the clinical characteristics, glycemic abnormalities, and the relationship between the initial glucose level and mortality in patients with sepsis. Methods This is a retrospective sub-analysis of a multicenter, prospective cohort study. Adult patients with severe sepsis (Sepsis-2) were divided into groups based on blood glucose categories (
Databáze: OpenAIRE
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