Proteins that interact with bacterial small RNA regulators
| Autor: | Christophe Pichon, Brice Felden |
|---|---|
| Přispěvatelé: | Institut d'Astrophysique de Paris (IAP), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Fonction, structure et inactivation d'ARN bactériens, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Lefevre, Annick |
| Rok vydání: | 2007 |
| Předmět: |
Riboswitch
regulatory RNAs Small RNA RNA Untranslated RNA-binding protein Biology Microbiology MESH: RNA Untranslated 03 medical and health sciences Bacterial small RNA Bacterial Proteins small RNAs [SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology [SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology RNA Messenger noncoding RNAs MESH: Bacterial Proteins MESH: RNA Messenger 030304 developmental biology Genetics MESH: Gene Expression Regulation Bacterial 0303 health sciences Bacteria 030306 microbiology RNA chaperone RNA-Binding Proteins RNA sequestering RNAs Gene Expression Regulation Bacterial Non-coding RNA Cell biology RNA Bacterial MESH: Bacteria RNA silencing MESH: RNA-Binding Proteins Infectious Diseases Transfer RNA MESH: RNA Bacterial |
| Zdroj: | FEMS Microbiology Reviews FEMS Microbiology Reviews, Wiley-Blackwell, 2007, 31 (5), pp.614-25. ⟨10.1111/j.1574-6976.2007.00079.x⟩ FEMS Microbiology Reviews, 2007, 31 (5), pp.614-25. ⟨10.1111/j.1574-6976.2007.00079.x⟩ |
| ISSN: | 1574-6976 0168-6445 |
| DOI: | 10.1111/j.1574-6976.2007.00079.x |
| Popis: | International audience; Small regulatory RNAs have been identified in a wide range of organisms, where they modify mRNA stability, translation or protein function. Small RNA regulators (sRNAs) either pair with mRNA targets or modify protein activities. Here we discuss current knowledge of the various proteins that interact with RNA regulators and review the physiologic implications of sRNA-protein complexes in DNA, RNA and protein metabolism, as well as in RNA and protein quality control in prokaryotes. Proteins that interact with the sRNAs can possess catalytic activity, induce conformational changes of the sRNA, or be sequestered by the sRNA to prevent the action of the protein. |
| Databáze: | OpenAIRE |
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