Clinical Features and Racial/Ethnic Differences Among the 3020 Participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) Trial

Autor: Irene Meissner, Kalyani Peri, Antonio Arauz, Pablo E. Pergola, Leslie A. McClure, Lesly A. Pearce, Carlos S. Kase, E. J. Pretell, Ana Roldan, Lisa H. Irby, Marie-France Benavente, Robin Conwit, Oscar H. Del Brutto, Robert G. Hart, Brett C. Meyer, Jeff M. Szychowski, Carole L. White, Christopher S. Coffey, Oscar R. Benavente, Bart M. Demaerschalk
Rok vydání: 2013
Předmět:
Male
Time Factors
Blood Pressure
Risk Factors
Ethnicity
Prevalence
Secondary Prevention
Stroke
Smoking
Rehabilitation
Hispanic or Latino
Middle Aged
Magnetic Resonance Imaging
Clopidogrel
Treatment Outcome
Hypertension
Cohort
Platelet aggregation inhibitor
Drug Therapy
Combination

Female
Racial/ethnic difference
Cardiology and Cardiovascular Medicine
medicine.medical_specialty
Ticlopidine
Lacunar stroke
Drug Administration Schedule
White People
Article
Internal medicine
Diabetes mellitus
Diabetes Mellitus
medicine
Humans
Antihypertensive Agents
Aged
Chi-Square Distribution
Aspirin
business.industry
Racial Groups
South America
medicine.disease
Black or African American
Blood pressure
Spain
North America
Physical therapy
Surgery
Neurology (clinical)
business
Chi-squared distribution
Platelet Aggregation Inhibitors
Zdroj: Journal of Stroke and Cerebrovascular Diseases. 22:764-774
ISSN: 1052-3057
Popis: This study examined the baseline characteristics, racial/ethnic differences, and geographic differences among participants in the Secondary Prevention of Small Subcortical Strokes (SPS3) study. The SPS3 trial enrolled patients who experienced a symptomatic small subcortical stroke (lacunar stroke) within the previous 6 months and an eligible lesion on detected on magnetic resonance imaging. The patients were randomized, in a factorial design, to antiplatelet therapy (aspirin 325 mg daily plus clopidogrel 75 mg daily vs aspirin 325 mg daily plus placebo) and to one of two levels of systolic blood pressure targets ("intensive" [
Databáze: OpenAIRE