Incidence and risk factors for rectovaginal fistula after low anterior resection for rectal cancer

Autor: Yasushi Ichikawa, Kazuteru Watanabe, Shuhei Kaida, Ryusei Matsuyama, Mari S. Oba, Nobuyuki Kamimukai, Itaru Endo, Shunichi Osada, Jun Watanabe, Hidetaka Shima, Daisuke Kawaguchi, Noriyuki Kamiya, Mitsuyoshi Ota, Hirotoshi Akiyama, Atsushi Ishibe
Rok vydání: 2015
Předmět:
Zdroj: International Journal of Colorectal Disease. 30:1659-1666
ISSN: 1432-1262
0179-1958
DOI: 10.1007/s00384-015-2340-5
Popis: The rectovaginal fistula (RVF) is a rare complication after low anterior resection (LAR) for rectal cancer. The aim of this study was to evaluate the risk factors for RVF after LAR for rectal cancer. This was a retrospective multi-institution study of 371 female rectal cancer patients who underwent LAR with anastomosis between January 2007 and December 2011. Patient-, tumor-, and surgery-related variables were examined by univariate and multivariate analyses. The overall RVF rate was 3.0 % (11/371). The RVF was diagnosed on median postoperative day 83 (15–766). In 81.8 % (9/11) of the patients, the diagnosis of RVF was made after hospital discharge. Multivariate analysis identified prognostic nutritional index (PNI; odds ratio (OR) 6.97; 95 % confidence interval (CI) 1.47–33.08; P = 0.015), preoperative chemotherapy (OR 27.31; CI 3.49–213.62; P = 0.002), tumor size (OR 5.90; CI 1.04–33.47; P = 0.045), intraoperative bleeding (OR 13.91; CI 1.34–144.42; P = 0.027), and lateral lymph node dissection (OR 4.92; CI 1.02–23.63; P = 0.045) as independent risk factors for RVF after LAR. Risk factors of RVF were PNI (
Databáze: OpenAIRE