Dexmedetomidine with magnesium sulphate as adjuvants in caudal block to augment anaesthesia and analgesia in paediatric lower abdominal surgeries
| Autor: | Ragai S Hanna, Emad Zarief Kamel, Mohamed Amir Fathy Riad, Jehan Ahmed Sayed, Sayed Kaoud Abd-Elshafy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Bupivacaine
business.industry Magnesium medicine.medical_treatment chemistry.chemical_element 030208 emergency & critical care medicine law.invention lcsh:RD78.3-87.3 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Randomized controlled trial chemistry 030202 anesthesiology law lcsh:Anesthesiology Anesthesia FLACC scale medicine General anaesthesia Dexmedetomidine Augment business Saline medicine.drug |
| Zdroj: | Egyptian Journal of Anaesthesia, Vol 34, Iss 4, Pp 115-122 (2018) |
| ISSN: | 1110-1849 |
| Popis: | Purpose: To investigate the implication of dexmedetomidine and magnesium sulphate addition to bupivacaine in caudal anesthesia in paediatric lower abdominal surgeries. Study design: Randomized controlled trial. Setting: Paediatric University Hospital. Subjects: 120 children undergoing surgeries in the lower half of the body under general anaesthesia with a supplementary caudal block using 1 ml/kg bupivacaine 0.25%. Methods: Participants were randomly allocated into four groups; group C (saline as an additive to bupivacaine), group MG (50 mg magnesium sulphate added to bupivacaine), group D (1 µg/kg dexmedetomidine added to bupivacaine), and group MGD (the same doses of both dexmedetomidine and magnesium sulphate were added to bupivacaine). Time to first analgesia request (1ry outcome), and pain assessment by The Face, Legs, Activity, Cry, Consolability (FLACC) score just after recovery, then every 30 min in the early two hours, then at the 4th, 6th, 12th,18th, and 24th hours were compared between the groups. Results: Time to first analgesia request was significantly longer in the three study groups compared to group C with p |
| Databáze: | OpenAIRE |
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