Acute sporadic hepatitis in Sudanese children
| Autor: | N. Al-Huda Atallah, Kenneth C. Hyams, A. El-Tigani, M. A. Al-Arabi, M. A. M. Hussain, Michael C. McCarthy |
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| Rok vydání: | 1991 |
| Předmět: |
Male
Herpesvirus 4 Human HBsAg Jaundice medicine.disease_cause Disease Outbreaks Sudan Risk Factors Virology medicine Humans Child Hepatitis B virus Hepatitis Hepatitis B Surface Antigens biology business.industry Infant Hepatitis A medicine.disease biology.organism_classification Hepatitis C Infectious Diseases Immunoglobulin M Social Class Hepadnaviridae Child Preschool Viral disease medicine.symptom business Viral hepatitis Biomarkers |
| Zdroj: | Journal of Medical Virology. 33:73-76 |
| ISSN: | 1096-9071 0146-6615 |
| DOI: | 10.1002/jmv.1890330202 |
| Popis: | Eighty consecutive cases of acute viral hepatitis and 80 controls selected from a public pediatric clinic were entered into a study of acute sporadic hepatitis in Khartoum, Sudan. Study subjects were 14 years of age or younger and were mainly from a low socioeconomic level. Non-A, non-B hepatitis was diagnosed by exclusion in 35 (43.8%) patients, hepatitis A in 27 (33.8%), acute hepatitis B in 8 (10.0%), possible Epstein-Barr virus (EBV) hepatitis in 1 patient; and dual hepatitis A and B infection in 1 patient. Eight acute cases were positive for HBsAg but negative for anti-HBc IgM and anti-HAV IgM. Delta hepatitis was not identified in any study subject. A household case of jaundice and acquaintance with an individual outside of the household with jaundice during the prior 6 months were associated with non-A, non-B hepatitis. There was no association between parenteral exposure and non-A, non-B hepatitis. These findings suggest that enterically transmitted non-A, non-B hepatitis may be a major cause of acute sporadic hepatitis in children in this area, as well as a cause of epidemic hepatitis. |
| Databáze: | OpenAIRE |
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