Outcome of emergency percutaneous coronary intervention for acute ST-elevation myocardial infarction complicated by cardiac arrest
| Autor: | Aviv Mager, Daniel Murninkas, Ran Kornowski, Abid Assali, David Brosh, Hana Vaknin-Assa, Alexander Battler, Shimrit Ukabi |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Myocardial Infarction Risk Assessment Sudden death Risk Factors Coronary Circulation Internal medicine medicine Humans Prospective Studies cardiovascular diseases Myocardial infarction Angioplasty Balloon Coronary Emergency Treatment Aged business.industry Mortality rate Cardiogenic shock Age Factors Percutaneous coronary intervention Electrocardiography in myocardial infarction General Medicine Thrombolysis Middle Aged medicine.disease Cardiopulmonary Resuscitation Heart Arrest Treatment Outcome Conventional PCI Cardiology Female Cardiology and Cardiovascular Medicine business Glomerular Filtration Rate |
| Zdroj: | Coronary Artery Disease. 19:615-618 |
| ISSN: | 0954-6928 |
| DOI: | 10.1097/mca.0b013e32831381b4 |
| Popis: | Background The poor prognosis of primary percutaneous coronary intervention (PCI) in patients resuscitated from cardiac arrest complicating acute ST-segment elevation myocardial infarction (STEMI) may at least partly be explained by the common presence of cardiogenic shock. This study examined the impact of emergency primary PCI on outcome in patients with STEMI not complicated by cardiogenic shock who were resuscitated from cardiac arrest. Methods and results The study group included 948 consecutive patients without cardiogenic shock who underwent emergency primary PCI from 2001 to 2006 for STEMI. Twenty-one of them were resuscitated from cardiac arrest before the intervention. Data on background, clinical characteristics, and outcome were prospectively collected. There were no differences between the resuscitated and nonresuscitated patients in age, sex, infarct location, or left ventricular function. The total one-month mortality rate was higher in the resuscitated patients (14.3 vs. 3.4%, P=0.033), but noncardiac mortality accounted for the entire difference (14.3 vs. 1.2%, P=0.001), whereas cardiac mortality was similarly low in the two groups (0 vs. 2.0%, P=NS). Predictors of poor outcome in the resuscitated patients were older age (r=0.47, P=0.032), unwitnessed sudden death (r=0.44, P=0.04), longer interval between onset of cardiac arrest and arrival of a mobile unit (r=0.67, P=0.001) or to spontaneous circulation (r=0.65, P=0.001), low glomerular filtration rate (r=−0.50, P=0.02), and the initial thrombolysis in myocardial infarction grade of flow (r=−0.51, P=0.017). Conclusion Emergency PCI for STEMI not associated with cardiogenic shock exerts a similar effect on cardiac mortality in patients who were resuscitated from cardiac arrest and in those without this complication. The higher all-cause mortality rate among resuscitated patients is explained by noncardiac complications. |
| Databáze: | OpenAIRE |
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