Early experience with Watson for oncology in Korean patients with colorectal cancer
Autor: | Sun Jin Sym, Eui Joo Kim, Kwang An Kwon, Jun-Won Chung, Yoon Jae Kim, Jeong-Heum Baek, Jae Hee Cho, Kyoung Oh Kim, Won-Suk Lee, Hyun Sun Woo, Dong Kyun Park |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Oncology Male Colorectal cancer Adjuvant Chemotherapy Cancer Treatment Medical Oncology User-Computer Interface 0302 clinical medicine Medicine and Health Sciences Stage (cooking) Aged 80 and over Multidisciplinary Pharmaceutics Middle Aged Treatment Outcome 030220 oncology & carcinogenesis Practice Guidelines as Topic Medicine Female Colorectal Neoplasms Algorithms Research Article Adult Clinical Oncology medicine.medical_specialty Computer and Information Sciences Concordance Science Expert Systems Stage ii Rectal Cancer 03 medical and health sciences Cancer Chemotherapy Drug Therapy Diagnostic Medicine Internal medicine Republic of Korea Gastrointestinal Tumors medicine Cancer Detection and Diagnosis Humans Chemotherapy In patient Aged Neoplasm Staging Retrospective Studies Patient Care Team Colorectal Cancer Computing Systems business.industry Computers Reproducibility of Results Cancers and Neoplasms Retrospective cohort study Mean age medicine.disease Decision Support Systems Clinical Regimen 030104 developmental biology Interdisciplinary Communication Clinical Medicine business Software |
Zdroj: | PLoS ONE, Vol 14, Iss 3, p e0213640 (2019) PLoS ONE |
ISSN: | 1932-6203 |
Popis: | Background Watson for oncology (WFO) is a cognitive computing system providing decision support. We evaluated the concordance rates between the treatment options determined by WFO and those determined by a multidisciplinary team (MDT). Methods We reviewed the medical charts of patients diagnosed with colorectal cancer who visited the MDT at a single tertiary medical center from November 2016 to April 2017. WFO classified the treatment options for specific patients into three categories: ‘Recommended’, ‘For consideration’, and ‘Not recommended’. Concordance rates between the WFO- and MDT-determined chemotherapy options, and the factors that potentially influence the concordance rate, were analyzed. Results Sixty-nine patients with colorectal cancer met with the MDT from Nov. 2016 to Feb. 2017. The mean age of the patients was 62 years (range: 34–86 years), and more patients were male (47/69) than female. Of the 69 patients, 51 (73.9%) were diagnosed with colon cancer, of whom 46.4% received the same regimen recommendation from WFO (‘Recommended’) as they did from the MDT. After inclusion of the ‘For consideration’ category from WFO, the concordance rate increased to 87.0%. The concordance rate between MDT and NCCN guidelines was 97.1%, and that between the WFO and NCCN guidelines was 88.4%. The concordance rates between WFO and MDT were significantly lower in patients with stage II, IIIC, or IV disease (P |
Databáze: | OpenAIRE |
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